EvexiPEL® pellets, injections, oral capsules, sublingual troches, vaginal troches, creams and gels, patches
Fifteen to forty-five minutes depending on the delivery method selected
Minimal. A local anesthetic is used for pellet placement
Most patients return to normal activity the same day. Pellet placement carries short-term activity restrictions
Required before starting and repeated at follow-up intervals
Varies by individual, hormone type, and delivery method
Ongoing, with dose adjustments guided by follow-up testing and symptoms
When hormones shift out of balance, the effects rarely stay in one place. Energy, sleep, mood, concentration, body composition, and comfort can all change at once, and the pattern is often gradual enough that patients spend months assuming it is simply age or stress. Bioidentical Hormone Replacement Therapy in Littleton, CO, addresses those changes at the source by replenishing hormones with compounds that are structurally identical to the ones the body produces on its own.
What makes this therapy work is not the hormone alone but the precision behind it. Care at Artistry Skin & Hormone begins with laboratory testing and a full symptom history rather than a standard protocol, and the delivery method is chosen to match how a patient actually lives. Patients across Littleton, CO, choose from seven different delivery options, which means the plan can be adjusted as the body responds instead of locking into a single approach from day one.
Bioidentical Hormone Replacement Therapy uses plant-derived hormones that match the molecular structure of estrogen, progesterone, and testosterone as the human body produces them. That structural match is what separates Bioidentical therapy from older synthetic formulations, because hormones shaped like the body’s own bind to the same receptors and follow familiar metabolic pathways. The practical result for patients in Littleton, CO, is a therapy that can be dosed and adjusted with a high degree of individual control.
The therapy is most often used during perimenopause, menopause, and andropause, though it also applies to hormone decline that arrives earlier than expected. Testing establishes where levels actually sit, and treatment replenishes only what is genuinely low. Because compounded formulations can be prepared in strengths that off-the-shelf products do not offer, patients in Littleton, CO, are not restricted to fixed doses that may be too much or too little for their physiology.
Treatment starts with measurement rather than assumption. A detailed symptom review is paired with functional laboratory testing to establish baseline hormone levels, and related markers such as cortisol testing are often assessed alongside them, since adrenal and thyroid function influence how hormone symptoms present. Two patients in Littleton, CO, can describe identical fatigue and have entirely different underlying pictures.
Once results are in, a plan is built around three decisions: which hormones to replenish, at what dose, and through which delivery method. Each method releases hormone into the bloodstream on a different curve, so the choice shapes daily experience as much as the dose does. Pellets provide steady release over months, while creams, patches, and troches can be modified week to week.
Follow-up is where the therapy is actually refined. Repeat testing and symptom check-ins guide dose adjustments over the first several months, and most plans are revised at least once before they settle. Patients throughout Littleton, CO, also receive guidance on sleep, nutrition, movement, and stress, because hormone therapy performs better when the surrounding habits support it. Where testing points to broader gaps, customized supplement replacement may be added to the plan.
Hot flashes, night sweats, and temperature sensitivity are among the changes patients most often report improving.
Many patients in Littleton, CO, describe fewer afternoon crashes and less reliance on caffeine to get through the workday.
Progesterone in particular is associated with easier sleep onset and fewer overnight wakings for many patients.
Irritability, low mood tied to hormonal change, and the sensation of brain fog are commonly reported areas of improvement.
Dryness, thinning, and loss of elasticity often track with declining hormone levels and may respond as levels are restored.
Patients frequently report that maintaining muscle and moving comfortably feels more achievable once levels are addressed.
Therapy can be matched to schedule, preference, and tolerance rather than forcing one format on every patient in Littleton, CO.
Dosing is revisited as the body responds, so the therapy continues to fit as circumstances change.
Hormonal imbalance, perimenopause symptoms, menopause symptoms, hot flashes and night sweats, and irregular or changing menstrual cycles.
Chronic fatigue and low energy, mood swings and irritability, low mood associated with hormone changes, brain fog and difficulty concentrating, and poor sleep quality or insomnia.
Weight gain and difficulty losing weight, changes in body composition, loss of muscle mass, and joint aches or stiffness.
Low libido, along with vaginal dryness and discomfort.
Thinning hair, skin dryness, and loss of elasticity.
Low testosterone in men and women, and the cluster of energy, mood, strength, and libido changes associated with andropause.
Patients who recognize several of these together often find a fuller explanation on the hormonal imbalance page, which covers how these symptoms cluster and what testing looks for. Related patterns such as slow metabolism and low energy are addressed there as well.
Good candidates are adults experiencing symptoms consistent with declining or fluctuating hormones, confirmed by laboratory testing. That includes women in perimenopause and menopause, women who have had a hysterectomy or oophorectomy, and men with symptoms of low testosterone. Candidacy is established by results and symptoms together, since normal-range levels in a symptomatic patient still warrant a conversation.
Hormone therapy is not appropriate for everyone. Patients with a personal history of hormone-sensitive cancer, unexplained vaginal bleeding, active liver disease, or a history of blood clots or stroke require careful evaluation, and in many cases hormone therapy will not be recommended at all. Pregnancy and breastfeeding are exclusions. Every candidate in Littleton, CO, is reviewed against personal and family medical history before a plan is written, and patients who are not candidates are given other options rather than being turned away.
The first visit is a conversation and a blood draw. Symptoms, medical history, medications, sleep, stress, and goals are all reviewed, and laboratory work is ordered to establish baseline levels. Results typically return within about a week, and treatment does not begin until they have been reviewed together.
At the results visit, findings are explained in plain terms alongside a recommended starting protocol. Delivery method is selected at this point, weighing convenience, how steady a release is preferred, and how much adjustability a patient wants early on. Patients in Littleton, CO, leave this visit knowing what they are taking, why, and when the first follow-up will be.
For creams, patches, troches, and capsules, treatment begins at home with written instructions. For injections, patients are either treated in office or taught self-administration. Pellet insertion is performed in office and takes roughly fifteen minutes, described below in more detail.
The first follow-up generally falls between four and eight weeks in, with repeat labs to see how levels have responded. Adjustments are common at this stage and are a normal part of the process rather than a sign something has gone wrong. Once a plan is stable, most patients in Littleton, CO, move to periodic monitoring.
Some panels require morning collection or fasting. Instructions are provided when the order is placed.
Include over-the-counter products and anything taken irregularly, since several interact with hormone metabolism.
Hormone-sensitive cancers, clotting disorders, and cardiovascular events in close relatives all affect the recommendation.
Biotin supplements can interfere with certain assays. Stop as directed before the draw.
A short log of sleep, energy, mood, and cycle patterns gives the Littleton, CO, team a clearer starting picture than recall alone.
Patients scheduling pellet insertion should avoid strenuous exercise for several days afterward and should plan the appointment accordingly.
Consistency matters more than timing perfection. Creams and troches in particular depend on regular application.
Keep the site clean and dry, leave the dressing in place as instructed, and avoid soaking in tubs, pools, or hot tubs for the period specified.
Avoid heavy lower-body exercise and swimming for several days to reduce the risk of the pellet shifting or the site becoming irritated.
Mild bloating, breast tenderness, mood shifts, or spotting can occur in the early weeks as levels stabilize.
Notes on what changed and when make the follow-up visit far more productive.
Patients in Littleton, CO, should contact the office promptly about site redness or drainage, severe headache, chest pain, leg swelling, or unexplained bleeding.
Duration depends on delivery method. Pellets release over roughly three to five months in women and four to six months in men, with the exact interval varying by metabolism and activity level. Injections are typically weekly or every other week, creams and gels are applied daily, patches are changed once or twice weekly, and oral capsules and troches are taken daily.
Across every method, benefits continue only while therapy continues. Hormone levels return toward their untreated baseline once treatment stops, and symptoms generally follow, which is why Bioidentical Hormone Replacement Therapy in Littleton, CO, is presented as ongoing care rather than a course with a finish line.
Hormone metabolism depends heavily on digestive function, and addressing gut imbalances often improves how well hormone therapy is tolerated.
For patients whose primary concern is vaginal dryness or discomfort, FemTouch addresses tissue quality directly and pairs well with systemic therapy.
Where fatigue persists after hormone levels are addressed, B12 supports energy and cognitive function through a separate pathway.
Testing frequently reveals nutrient gaps that sit underneath hormone symptoms, and correcting them supports the broader plan.
Cortisol, micronutrient, and gut microbiome panels give a fuller picture when symptoms do not resolve as expected in Littleton, CO.
EvexiPEL® pellets are compounded hormone pellets roughly the size of a grain of rice, placed just beneath the skin of the upper hip or buttock through a small incision made under local anesthetic. The procedure takes about fifteen minutes, closes with adhesive strips rather than sutures, and is performed in the office. Patients across Littleton, CO, typically return to desk work the same day.
The appeal of pellets is steadiness. Rather than the peaks and troughs that can come with daily or weekly dosing, pellets release hormone gradually as blood flow carries it away, and delivery rises modestly with activity and metabolic demand. For patients who dislike remembering a daily routine, or who have not felt stable on creams or injections, that consistency is the main reason to choose them.
The tradeoff is worth understanding before committing. Once a pellet is placed, the dose cannot be reduced or adjusted, and it continues releasing until the body absorbs it over the following months. A patient who turns out to be sensitive to the dose has to wait it out, whereas a cream or patch could be changed within days. For that reason, many patients in Littleton, CO, begin with an adjustable method to establish the right dose, then move to pellets once the target is known. Others go directly to pellets after testing. Both routes are reasonable, and the decision is made together at the results visit.
| Method | How It Is Given | Frequency | Adjustability | Often Suits |
|---|---|---|---|---|
| EvexiPEL® Pellets | Placed under the skin in office | Every 3 to 6 months | Not adjustable once placed | Patients wanting steady levels and no daily routine |
| Injections | Intramuscular or subcutaneous | Weekly or biweekly | Adjustable each dose | Patients comfortable with needles who want dose control |
| Oral Capsules | Swallowed | Daily | Adjustable | Patients who prefer a simple pill routine |
| Sublingual Troches | Dissolved under the tongue | Daily, often twice | Adjustable | Patients who want to bypass first-pass liver metabolism |
| Vaginal Troches | Inserted vaginally | Daily or as directed | Adjustable | Patients whose main concern is local dryness and comfort |
| Creams and Gels | Applied to the skin | Daily | Highly adjustable | Patients starting therapy or fine-tuning a dose |
| Patches | Worn on the skin | Changed 1 to 2 times weekly | Adjustable at each change | Patients wanting steady delivery without a procedure |
Hormone care sits at the center of what Artistry Skin & Hormone does rather than at the edge of an aesthetics menu. That focus shows up in the depth of testing, the range of delivery options, and the willingness to adjust a plan until it is right for patients across Littleton, CO.
Founder Laura Carlsen, AGNP, Certified Laser Specialist, LE, is an Adult and Geriatric Nurse Practitioner with advanced training through WorldLink, A4M, The Kalish Institute, and Evexias.
Medical Director Dr. Douglas Minton is board-certified in Obstetrics and Gynecology and certified in Age Management Medicine through Cenegenics, so hormone protocols carry genuine clinical review.
Hormones are evaluated alongside gut function, nutrient status, stress, and sleep rather than in isolation.
Lab results are explained in plain language, and patients leave understanding what is being treated and why.
Every dose decision is anchored to testing and symptom tracking, not to a standard protocol.
Seven delivery methods are offered under one roof, so the plan fits the patient rather than the other way around.
Artistry Skin & Hormone proudly offers Bioidentical Hormone Replacement Therapy in Littleton, CO, welcoming patients from surrounding communities seeking hormone therapy. Our conveniently located office allows us to serve clients from:
Cost depends on which hormones are prescribed, the delivery method, and how much laboratory testing the plan requires. Pellets carry a higher per-visit cost but fewer visits, while creams and troches spread cost across monthly refills. Pricing is reviewed in full at the consultation before anything is ordered, and financing is available through Cherry and CareCredit, both detailed on the patient financing page.
Coverage varies considerably. Some laboratory testing may be billable to insurance, while compounded hormone preparations and pellet placement are frequently not covered. Patients are encouraged to check directly with their carrier, and the Littleton, CO, team can explain what a plan will cost out of pocket so there are no surprises.
The difference is how steadily the hormone enters the bloodstream and how easily the dose can be changed. Pellets deliver consistently for months but cannot be adjusted once placed. Creams, patches, and oral forms deliver on a shorter cycle and can be modified quickly. The comparison table above sets the seven options side by side.
Patients with a history of hormone-sensitive cancer, unexplained vaginal bleeding, active liver disease, or a history of blood clots or stroke require careful evaluation, and hormone therapy is often not recommended in those cases. Pregnancy and breastfeeding are exclusions. Candidacy is determined after a full history and lab review.
A baseline panel typically covers sex hormones, thyroid function, and metabolic markers, with cortisol and nutrient testing added where symptoms suggest it. Testing is repeated at follow-up so dosing decisions are based on measured response rather than guesswork.
Weight change is one of the more common concerns patients raise, and the honest answer is that it varies. Some patients notice changes early as the body adjusts. Because many factors influence weight alongside hormones, this is tracked as part of follow-up rather than treated as a guaranteed outcome in either direction.
Thinning hair is frequently reported alongside hormonal change, and some patients notice improvement as levels are addressed. Hair loss has many possible causes, so testing looks for thyroid and nutrient contributors as well before attributing it to hormones alone.
Timelines differ by symptom and delivery method. Sleep and hot flashes are often among the earlier changes patients report, while energy, mood, and body composition tend to take longer. The first follow-up at four to eight weeks is where progress is formally assessed.
Hormone therapy carries real risks and real benefits, and both depend on individual history. Compounded Bioidentical preparations are not FDA-approved, which is discussed openly during the consultation. Safety is managed through thorough screening, conservative starting doses, ongoing laboratory monitoring, and physician oversight.
Benefits continue while therapy continues, so most patients who choose to treat remain on some form of it. Duration is revisited regularly, and some patients reduce or stop over time. The decision is reviewed at every follow-up rather than set once at the start.

Gut health services focus on improving digestion, nutrient absorption, and immune balance. Addressing gut imbalances can positively impact energy, inflammation, skin health, and overall wellness.

Cardiovascular health support focuses on improving circulation, heart function, and metabolic balance. These services help patients reduce risk factors while supporting long-term heart health.

B12 injections help support energy levels, metabolism, mood, and cognitive function. This treatment is ideal for patients experiencing fatigue, low energy, or nutrient deficiencies that affect daily performance.